website background_edited_edited_edited_edited.jpg

CURRENT MEMBERS

Principal Investigator

Assistant Professor Ni Qianqian

Member of Italian Chemical Society 2024 - Present

B.Med., Nanjing University (Clinical Medicine)

PhD., Nanjing University (Medical Imaging and Nuclear medicine)

Postdoctoral Fellow, National Institutes of Health (Molecular Imaging and Nanomedicine)

Dr. Ni finished her PhD training at Nanjing University and National Institutes of Health (NIH, USA). After postdoc training from National Institute of Biomedical Imaging and Bioengineering (NIBIB)/NIH, she joined NUS School of Medicine and started her Assistant Professorship from 2021. Her research over the past five years focused on applying novel nanotechnologies and modification techniques for RNA therapeutics development, which has been published in prestigious journals such as Nat. Rev. Bioeng. (2025), Nat. Nanotechnol. (Accepted, 2025), Adv. Mater. (2024, 2025), Nat. Commun. (2023), Angew. Chem. Int. Ed. (2023). Dr. Ni is also leading several scientific projects granted by A*Star, MOE, NMRC, NRF, Singapore (>6 Million), and has been awarded the Rising Talents by Precision Nanomedicine (2024) and Emerging Investigator of Nanoscale (2026).

AWARDS:

Rising Talents of Precision Nanomedicine 2024

Welman’s Award for Doctoral Thesis Excellence 2018

Shi Le Hui Fellowship 2017-2018

National Doctoral Fellowship 2016

NJU Graduate Scholarship 2014

People’s Scholarship 2012-2013

Basic Subject Forum Award 2012

People’s Scholarship 2011-2012

NJU Excellent Teaching Assistant Award 2009-2010

Mail

qqian.ni@nus.edu.sg

Research Fundings

Current Funding Support

2025-2029, Ni Qianqian, Team PI, Generative AI models for the creation and delivery of mRNA vaccine, NRF AI4S, S$9,000,000.00
2025-2028, Ni Qianqian, Lead PI, Lipid nanoparticle platform technology for targeted mRNA delivery, A*Star NATi N05, S$3,137,763.00
2025-2028, Ni Qianqian, Lead PI, An improved lipid nanoparticle technology for folded messenger RNA delivery and gene editing, MOE Tier 2, $1,032,150.00
2023-2026, Ni Qianqian, Lead PI, Design of nucleic acid immune agonist delivery platform technology to elicit potent and safe anti-tumor immunity, NMRC YIRG, $325,000.00
2024-2025, Ni Qianqian, Lead PI, T cell targeted dendrimer nanoparticles mediate in-vivo mRNA delivery for human CAR-T engineering, Merlion Program 2024, S$40,000.00
2023-2028, Ni Qianqian, Co-PI, In situ therapeutic nanovaccine for personalized cancer immunotherapy, NMRC IRG, $1,250,000.00
2023-2028, Ni Qianqian, Co-PI, Development of individualized cancer vaccine. NRF Competitive Research Programme, $8,000,000.00
2022-2025, Ni Qianqian, PI, Coordinated mRNA-Mn2+ Nanovaccine for STING-mediated Cancer Immunotherapy, MOE Tier 1, $250,000.00
2022-2026, Ni Qianqian, PI, Albumin based nanovaccine to potentiate cancer immunotherapy, NUS Start-up, $1,000,000.00
Completed Research Support
2023-2024, Ni Qianqian, PI, Dimeric albumin binding technology for immunomodulation. Wuxi apptec-nus solitaire initiative. S$20,000.00

Research Fellow

Li Benhao

benhaoli@nus.edu.sg

Mail

Benhao obtained his Bachelor's Degree from Northwest A&F University. Then, he received his PhD. Degree from Fudan University in 2020. His current research focuses on NIR bioimaging biosensing, and gene therapy.

Hu Haijun

huhaijunjxnc@163.com

Mail

Haijun joined Dr. Ni's lab in Jan. 2024, where he works on mRNA vaccine for cancer treatment. Before joining NUS, he was a postdoctoral scholar at Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences from 2021 to 2024. He received the PhD degree from Shanghai Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences in 2020, the M.Sc. degree from Kunming Institute of Botany, Chinese Academy of Sciences in 2015, and the B.Sc. degree from Nanchang University in 2008.

He Xidong

xd_he@nus.edu.sg

Mail

Xidong obtained his Bachelor’s Degree from Huazhong University of Science and Technology in 2018. He subsequently got his Ph.D. Degree from Changchun Institute of Applied Chemistry, Chinese Academy of Sciences in 2024. He joined Dr. Ni’s lab in Jan. 2025, and focus on design of lipid nanoparticle for respiratory mucosal delivery of mRNA vaccines.

Yi Li

_

Mail

Yi Li received her bachelor’s degree in Pharmaceutical Engineering from Sichuan University in 2020, and her Ph.D. from the National Center for Nanoscience and Technology in 2025. Her research focuses on the design and optimization of nanomedicines, gene drug delivery, and cancer immunotherapy.

Graduate Student

Yang Bowei

e0788032@u.nus.edu

Mail

Bowei graduated from Beijing University of Chemical Technology in 2021 where he obtained his B.Sc. in Material Science. He joined Dr. Ni’s lab as PHD student to study lipid nanoparticles (LNP) synthesis for mRNA delivery and CRISPR-Cas9 delivery for gene editing.

Shi Keming

shikeming@u.nus.edu

Mail

Keming graduated from National University of Singapore in 2025 where he obtained a B.Sc. in Life Science. He joined Dr. Ni's lab as a PhD student to study lipid nanoparticles (LNP) synthesis and applications in mRNA vaccine delivery.

Lim Hsin Thong

hsint_lim@u.nus.edu

Mail

Lim Hsin Thong graduated from Zhejiang University with a Bachelor’s degree in Bioengineering. She joined Dr. Ni’s lab in August 2025 as a Capstone Project Master’s student, with a research focus on RNA delivery and gene editing.

Ho Zi Zong

e1520537@u.nus.edu

Mail

Zi Zong holds a BSc in Life Sciences from NUS and is currently an R&D Manager at Lion TCR Pte Ltd. He joined Dr. Ni’s laboratory in August 2025 as a part-time MSc student to conduct research on the screening and validation of lipid nanoparticle (LNP) formulations predicted by AI models.

Li Zijie

e1554408@u.nus.edu

Mail

Li Zijie graduated from Shenzhen MSU-BIT University with a Bachelor of Science degree. He joined Ni’s lab as a master student in 2025, focusing on in vivo CAR T cell therapy.

Research Assistant

Ong Yen Hui

Mail

yenhui.o@nus.edu.sg

Yen Hui graduated from University of Tunku Abdul Rahman, Malaysia, where she obtained her B.Sc. (Honours) in Biomedical Science (2014) and M.Sc. in Molecular Biology (2019). Her current work in Dr Ni's lab is focusing on cancer immunology, particularly mRNA nanomedicine-based gene therapy.

Wu Zhaoming

Mail

e1322563@u.nus.edu

Zhaoming graduated from Shandong University in 2023, where he obtained his B.Sc. in Biological Science. He joined in Dr. Ni's lab as Master Student, focusing on the design and delivery of lipid nanoparticle-mRNA vaccines.

Li Xu

Mail

rogerli@hnu.edu.cn

Li Xu graduated from Hunan University in 2024, where he obtained his B.Sc. in Chemistry and M.Sc. in Analytical Chemistry. He joined Dr. Ni’s lab in Nov. 2024, where he works on nanomedicine delivery for cancer immunotherapy.

Fan Bangda

Mail

fanbd99@nus.edu.sg

Fan Bangda graduated from Dalian University of Technology in 2024, where he obtained his B.Sc. and M.Sc. in Bioengineering. He joined Dr. Ni’s lab in June 2025, where his research focuses on leveraging circular RNA for the development of novel RNA-based therapeutic strategies.

NI LAB
NUS Diagnostic Radiology

CURRENT MEMBERS

Principal Investigator

Assistant Professor Ni Qianqian

Member of Italian Chemical Society 2024 - Present

qqian.ni@nus.edu.sg

Research Fundings

Current Funding Support

Research Fellow

benhaoli@nus.edu.sg

huhaijunjxnc@163.com

xd_he@nus.edu.sg

_

Graduate Student

e0788032@u.nus.edu

shikeming@u.nus.edu

hsint_lim@u.nus.edu

e1520537@u.nus.edu

e1554408@u.nus.edu

Research Assistant

yenhui.o@nus.edu.sg

e1322563@u.nus.edu

rogerli@hnu.edu.cn

fanbd99@nus.edu.sg

NMRC YIRG

NRF Competitive Research Programme

NMRC IRG

WUXI APPTEC-NUS

MOE-TIER

NUS Start-up

NUS-Shawn Chen Lab

NUS invention ID (2023-019)

NUS invention ID (2022-171)